Payload Information
General Information of This Payload
| Payload ID | PAY0WLXJM |
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|---|---|---|---|---|---|---|
| Name | ZD06519 |
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| Synonyms |
ZD06519
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| Target(s) | DNA topoisomerase 1 (TOP1) | |||||
| Structure |
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| Formula | C25H24FN3O7 |
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| Isosmiles | CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc(F)c(C)cc1c2CNC(=O)OCCO |
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| InChI |
InChI=1S/C25H24FN3O7/c1-3-25(34)17-7-20-21-15(10-29(20)22(31)16(17)11-36-23(25)32)14(9-27-24(33)35-5-4-30)13-6-12(2)18(26)8-19(13)28-21/h6-8,30,34H,3-5,9-11H2,1-2H3,(H,27,33)
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| InChIKey |
SJLICXIYNPAXHJ-UHFFFAOYSA-N
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| Pharmaceutical Properties | Molecule Weight |
497.479 |
Polar area |
139.98 |
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Complexity |
36 |
xlogp Value |
1.74562 |
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Heavy Count |
36 |
Rot Bonds |
5 |
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Hbond acc |
9 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload
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