Linker Information
General Information of This Linker
| Linker ID |
LIN0YIZVG
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|---|---|---|---|---|---|---|
| Linker Name |
Mc-Gly-Gly-Phe-Gly-AM
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C26H34N6O7
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| Isosmiles |
CNC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)CCCCCN1C(=O)C=CC1=O
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| InChI |
InChI=1S/C26H34N6O7/c1-27-21(34)15-30-26(39)19(14-18-8-4-2-5-9-18)31-23(36)17-29-22(35)16-28-20(33)10-6-3-7-13-32-24(37)11-12-25(32)38/h2,4-5,8-9,11-12,19H,3,6-7,10,13-17H2,1H3,(H,27,34)(H,28,33)(H,29,35)(H,30,39)(H,31,36)
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| InChIKey |
LETKGXXMROUGGW-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
542.593
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Polar area
|
182.88
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Complexity
|
39
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xlogp Value
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-1.7061
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Heavy Count
|
39
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Rot Bonds
|
16
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Hbond acc
|
7
|
Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker
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