Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0FXFDD
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| ADC Name |
DMOT4039A
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| Synonyms |
AMA-MMAE; DMOT 4039A; DMOT 4039A, RG760 0; DMOT-4039A; DMOT4039A; Monoclonal antibody-drug conjugate (Monsah University); RG 7600; RG-7600; RG7600
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| Organization |
Monash University
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| Drug Status |
Phase 1 (Terminated)
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| Indication |
In total 2 Indication(s)
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| Drug-to-Antibody Ratio |
3.5
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| Structure |
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| Antibody Name |
Humanized IgG1 Anti-MSLN mAb h7D9.v3
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Antibody Info | ||||
| Antigen Name |
Mesothelin (MSLN)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random Cysteines
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| Combination Type |
vedotin
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