Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0FWCOG
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ADC Name |
CD25-ADC
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Drug Status |
Investigative
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Indication |
In total 1 Indication(s)
Colon cancer [ICD11:2B90]
Investigative
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Drug-to-Antibody Ratio |
2.1
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Antibody Name |
Anti-CD25 mAb PC61
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Antibody Info | ||||
Antigen Name |
Interferon-stimulated gene 20 kDa protein (ISG20)
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Antigen Info | ||||
Payload Name |
SG3199
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Payload Info | ||||
Therapeutic Target |
Human Deoxyribonucleic acid (hDNA)
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Target Info | ||||
Linker Name |
Mal-PEG8-Val-Ala-PABC
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Linker Info | ||||
Conjugate Type |
SG3249 is conjugated to the free sulfhydryl group obtained by reduction of cysteine on mAb in a random coupling.
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Combination Type |
SG3249
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