Antigen Information
General Information of This Antigen (ID: TAR0VQYAS)
| Antigen Name | Interferon-stimulated gene 20 kDa protein (ISG20) |
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| Gene Name | ISG20 |
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| Gene ID | ||||||
| Synonym | HEM45; Estrogen-regulated transcript 45 protein;Promyelocytic leukemia nuclear body-associated protein ISG20 |
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| Sequence |
MAGSREVVAMDCEMVGLGPHRESGLARCSLVNVHGAVLYDKFIRPEGEITDYRTRVSGVT
PQHMVGATPFAVARLEILQLLKGKLVVGHDLKHDFQALKEDMSGYTIYDTSTDRLLWREA KLDHCRRVSLRVLSERLLHKSIQNSLLGHSSVEDARATMELYQISQRIRARRGLPRLAVS D Click to Show/Hide
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| Family | EPCAM family |
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| Function |
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
Anti-CD25 mAb D265A
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
Anti-CD25 ADC 12-1
[1]
|
Anti-CD25 ADC 12-1 payload |
Undisclosed |
Anti-CD25 ADC 12-1 linker |
|
|
Anti-CD25 ADC 2-7
[1]
|
Anti-CD25 ADC 2-7 payload |
Undisclosed |
Anti-CD25 ADC 2-7 linker |
|
|
Anti-CD25 ADC 3-4
[1]
|
Anti-CD25 ADC 3-4 payload |
Undisclosed |
Anti-CD25 ADC 3-4 linker |
|
|
Anti-CD25 ADC 4-3
[1]
|
Anti-CD25 ADC 4-3 payload |
Undisclosed |
Anti-CD25 ADC 4-3 linker |
|
|
Anti-CD25 ADC 5-3
[1]
|
Anti-CD25 ADC 5-3 payload |
Undisclosed |
Anti-CD25 ADC 5-3 linker |
|
|
Anti-CD25 ADC 6-2
[1]
|
Anti-CD25 ADC 6-2 payload |
Undisclosed |
Anti-CD25 ADC 6-2 linker |
|
|
Anti-CD25 ADC 7-1
[1]
|
Anti-CD25 ADC 7-1 payload |
Undisclosed |
Anti-CD25 ADC 7-1 linker |
|
|
Anti-CD25 ADC 8-5
[1]
|
Anti-CD25 ADC 8-5 payload |
Undisclosed |
Anti-CD25 ADC 8-5 linker |
|
|
Anti-CD25 ADC 9-4
[1]
|
Anti-CD25 ADC 9-4 payload |
Undisclosed |
Anti-CD25 ADC 9-4 linker |
|
|
Anti-CD25 ADC 10-1
[1]
|
Anti-CD25 ADC 10-1 payload |
Undisclosed |
Anti-CD25 ADC 10-1 linker |
|
|
Anti-CD25 ADC 11-5
[1]
|
Anti-CD25 ADC 11-5 payload |
Undisclosed |
Anti-CD25 ADC 11-5 linker |
|
|
Anti-CD25 ADC 12-3
[1]
|
Anti-CD25 ADC 12-3 payload |
Undisclosed |
Anti-CD25 ADC 12-3 linker |
|
|
Anti-CD25 ADC 13-7
[1]
|
Anti-CD25 ADC 13-7 payload |
Undisclosed |
Anti-CD25 ADC 13-7 linker |
|
|
Anti-CD25 ADC 14-5
[1]
|
Anti-CD25 ADC 14-5 payload |
Undisclosed |
Anti-CD25 ADC 14-5 linker |
|
|
Anti-CD25 ADC 15-5
[1]
|
Anti-CD25 ADC 15-5 payload |
Undisclosed |
Anti-CD25 ADC 15-5 linker |
|
|
Anti-CD25 ADC 16-5
[1]
|
Anti-CD25 ADC 16-5 payload |
Undisclosed |
Anti-CD25 ADC 16-5 linker |
|
|
Anti-CD25 ADC 17-2
[1]
|
Anti-CD25 ADC 17-2 payload |
Undisclosed |
Anti-CD25 ADC 17-2 linker |
|
|
Anti-CD25 ADC 18-3
[1]
|
Anti-CD25 ADC 18-3 payload |
Undisclosed |
Anti-CD25 ADC 18-3 linker |
|
|
Anti-CD25 ADC 19-5
[1]
|
Anti-CD25 ADC 19-5 payload |
Undisclosed |
Anti-CD25 ADC 19-5 linker |
|
|
Anti-CD25 ADC 20-5
[1]
|
Anti-CD25 ADC 20-5 payload |
Undisclosed |
Anti-CD25 ADC 20-5 linker |
|
|
Anti-CD25 ADC 21-5
[1]
|
Anti-CD25 ADC 21-5 payload |
Undisclosed |
Anti-CD25 ADC 21-5 linker |
Anti-CD25 mAb PC61
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
CD25-ADC
[2]
|
SG3199 |
Human Deoxyribonucleic acid (hDNA) |
Mal-PEG8-Val-Ala-PABC |
Anti-CD25 mAb RFT5
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
RFT5-SMPT-dgA
|
Deglycosylated ricin A-chain (dgA) |
Undisclosed |
Succynimidyloxycarbonyl-alpha-methyl-alpha- (2-pyridyl-dithio) toluene (SMPT) |
Basiliximab
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
Basiliximab sarotalocan
[3]
|
Undisclosed |
Undisclosed |
Undisclosed |
Undisclosed
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
Anti-CD25-IR700 conjugate (Rakuten Medical)
[4]
|
IRDye 700DX |
Undisclosed |
Undisclosed |
References