Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0FRBDJ
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| ADC Name |
39410752 ADC (12)
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| Synonyms |
ADC (12)
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| Organization |
Ajinomoto Co., Inc.; Ajinomoto Bio-Pharma Services.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
10.8
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| Structure |
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| Antibody Name |
Trastuzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-EVC-PAB
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Linker Info | ||||
| Conjugate Type |
Site-specific bioconjugation at Trastuzumab-Lys248-thiol
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| Combination Type |
Mc-EVC-PAB-MMAE
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