Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0ESBEE
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| ADC Name |
wO2023232144A1ADC33
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| Synonyms |
WO2023232144A1ADC33
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| Organization |
CANWELL BIOTECH LIMITED
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
4.55
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| Structure |
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| Antibody Name |
Avelumab
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Antibody Info | ||||
| Antigen Name |
Programmed cell death 1 ligand 1 (CD274)
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Antigen Info | ||||
| Payload Name |
WO2025015586A1, ADC22, Payload
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase I (TOP1)
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Target Info | ||||
| Linker Name |
SMCC
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
(1r,4r)-N- (4- ((4-amino-2-butyl-7- (dimethylphosphoryl)-1H-imidazo[4,5-c]quinolin-1-yl)oxy)butyl)-4- ((2,5-dioxo-2,5-dihydro-1H-pyrrol-1- yl)methyl)cyclohexane-1-carboxamide
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