Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0EKESB
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| ADC Name |
CN106714844B ADC-105
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| Synonyms |
ADC-105
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| Organization |
Genentech Inc
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
1.7
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| Structure |
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| Antibody Name |
GM15.33 HC A118C
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Antibody Info | ||||
| Antigen Name |
Myeloid cell surface antigen CD33 (CD33)
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Antigen Info | ||||
| Payload Name |
PNU-159682
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
CN106714844B-ADC-105-linker
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
CN106714844B-ADC-105-linker-PNU-159682
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