Linker Information
General Information of This Linker
| Linker ID |
LIN0XQZVC
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| Linker Name |
CN106714844B-ADC-105-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C14H21N3O4S2
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| Isosmiles |
CN(CCN(C)C(OCC(SSC1=CC=CC=N1)C)=O)C(O)=O
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| InChI |
InChI=1S/C14H21N3O4S2/c1-11(22-23-12-6-4-5-7-15-12)10-21-14(20)17(3)9-8-16(2)13(18)19/h4-7,11H,8-10H2,1-3H3,(H,18,19)
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| InChIKey |
JVMWESXKECUGLG-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
359.473
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Polar area
|
82.97
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Complexity
|
468.0714946
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xlogp Value
|
2.8886
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Heavy Count
|
23
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Rot Bonds
|
8
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Hbond acc
|
6
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Hbond Donor
|
1
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Each Antibody-drug Conjugate Related to This Linker