Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0DFQML
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| ADC Name |
TF-mAb-H38-DM1
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| Synonyms |
TF mAb H38 DM1
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| Organization |
Fudan university
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| Drug Status |
Investigative
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| Indication |
In total 4 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Investigative
Glioblastoma [ICD11:2A00]
Investigative
Lung cancer [ICD11:2C25]
Investigative
Pancreatic cancer [ICD11:2C10]
Investigative
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| Drug-to-Antibody Ratio |
3-4
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| Structure |
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| Antibody Name |
TF-mAb-H38
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Antibody Info | ||||
| Antigen Name |
Tissue factor (F3)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
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Linker Info | ||||
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