Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0CREXS
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| ADC Name |
39143910 ADC 40
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| Synonyms |
ADC 40
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| Organization |
The University of Auckland.; University of Otago.; Victoria University of Wellington.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
2.2
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| Structure |
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| Antibody Name |
Cetuximab
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Antibody Info | ||||
| Antigen Name |
Epidermal growth factor receptor (EGFR)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
1- (4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl (Dde) based linker
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Linker Info | ||||
| Conjugate Type |
Site-specific conjugation via re-bridging.
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