Linker Information
General Information of This Linker
| Linker ID |
LIN0SQYRJ
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| Linker Name |
1- (4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl (Dde) based linker
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| Linker Type |
Azido Reduction-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H36N6O6
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| Isosmiles |
CC(CC(/C1=C(NC2=CC=C(CO)C=C2)\CC[C@H](N=[N+]=[N-])C(NCCCCCN3C(C=CC3=O)=O)=O)=O)(CC1=O)C
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| InChI |
InChI=1S/C29H36N6O6/c1-29(2)16-23(37)27(24(38)17-29)21(32-20-8-6-19(18-36)7-9-20)10-11-22(33-34-30)28(41)31-14-4-3-5-15-35-25(39)12-13-26(35)40/h6-9,12-13,22,32,36H,3-5,10-11,14-18H2,1-2H3,(H,31,41)/t22-/m0/s1
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| InChIKey |
SYPAZWCNCZCAQH-QFIPXVFZSA-N
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| Pharmaceutical Properties |
Molecule Weight
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564.643
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Polar area
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181.64
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Complexity
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1205.358937
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xlogp Value
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3.4737
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Heavy Count
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41
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Rot Bonds
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14
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Hbond acc
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8
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker