Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0CPNIE
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| ADC Name |
DS6-DM1
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| Synonyms |
DS6DM1; DS6 DM1
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| Organization |
ImmunoGen, Inc.
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| Drug Status |
Clinical candidate
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| Indication |
In total 1 Indication(s)
Solid tumors [ICD11:2A00-2A0Z|2B50-2F9Z]
Clinical candidate
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| Structure |
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| Antibody Name |
Anti-MUC1 mAb DS6
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Antibody Info | ||||
| Antigen Name |
Mucin-1 (MUC1)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
N-succinimidyl 4-(2-pyridyldithio) butanoate (SPDB)
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Linker Info | ||||
| Conjugate Type |
Lysine residue on the antibody is conjugated via an amide bond to the linker-payload moiety.
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| Combination Type |
Ravtansine
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