Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0AKFYV
|
|||||
---|---|---|---|---|---|---|
ADC Name |
Raludotatug deruxtecan
|
|||||
Synonyms |
Raludotatug deruxtecan
Click to Show/Hide
|
|||||
Drug Status |
Investigative
|
|||||
Drug-to-Antibody Ratio |
8
|
|||||
Structure | ||||||
Antibody Name |
Raludotatug
|
Antibody Info | ||||
Antigen Name |
Cadherin-6 (CDH6)
|
Antigen Info | ||||
Payload Name |
DX-8951 derivative (DXd)
|
Payload Info | ||||
Therapeutic Target |
DNA topoisomerase 1 (TOP1)
|
Target Info | ||||
Linker Name |
Mc-Gly-Gly-Phe-Gly
|
Linker Info | ||||
Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
|
|||||
Combination Type |
Deruxtecan
|
If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.