Antigen Information

General Information of This Antigen (ID: TAR0HELFC)
Antigen Name
Delta-like protein 3 (DLL3)
Gene Name
DLL3
Gene ID
10683
Synonym
Drosophila Delta homolog 3
Sequence
MVSPRMSGLLSQTVILALIFLPQTRPAGVFELQIHSFGPGPGPGAPRSPCSARLPCRLFF
RVCLKPGLSEEAAESPCALGAALSARGPVYTEQPGAPAPDLPLPDGLLQVPFRDAWPGTF
SFIIETWREELGDQIGGPAWSLLARVAGRRRLAAGGPWARDIQRAGAWELRFSYRARCEP
PAVGTACTRLCRPRSAPSRCGPGLRPCAPLEDECEAPLVCRAGCSPEHGFCEQPGECRCL
EGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTC
PRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQ
PCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALG
FGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAP
PGLRPGDPQRYLLPPALGLLVAAGVAGAALLLVHVRRRGHSQDAGSRLLAGTPEPSVHAL
PDALNNLRTQEGSGDGPSSSVDWNRPEDVDPQGIYVISAPSIYAREVATPLFPPLHTGRA
GQRQHLLFPYPSSILSVK

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Function
Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.

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Uniprot Entry
DLL3_HUMAN
HGNC ID
HGNC:2909
KEGG ID
hsa:10683
Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens
ADC Name Payload Target Linker ADC Info
JP7560255B2 ControlADC52 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
Anti-DLL3 antibody
 Antibody Info 
ADC Name Payload Target Linker ADC Info
SYS6040
Undisclosed
Undisclosed
A cleavable linker
 ADC Info 
FZ-AD005
DXd
DNA topoisomerase 1 (TOP1)
Mc-Val-Ala-PABC double self-immolative linker
 ADC Info 
Anti-DLL3 mAb
 Antibody Info 
ADC Name Payload Target Linker ADC Info
BL-M14D1 [2]
Ed-04
DNA topoisomerase 1 (TOP1)
Gly-Mal-Gly-Gly-Phe-Gly
 ADC Info 
IBI3009
NT1
DNA topoisomerase 1 (TOP1)
Undisclosed
 ADC Info 
Antibody of AMG595
 Antibody Info 
ADC Name Payload Target Linker ADC Info
JP7623413B2 ExampleADC61 [3]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
Glimatamab
 Antibody Info 
ADC Name Payload Target Linker ADC Info
JP7560255B2 ControlADC55 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
Rovalpituzumab
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Rovalpituzumab tesirine
SG3199 (SC-DR002)
Human deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala-PABC
 ADC Info 
SC-002
SG3199 (SC-DR002)
Human deoxyribonucleic acid (hDNA)
Val-Ala dipeptide linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.10-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.10-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.10-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.10-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.10-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.101-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.101-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.101-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.101-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.101-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.103-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.103-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.103-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.103-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.103-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.104-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.104-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.104-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.104-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.104-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.105-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.105-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.105-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.105-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.105-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.106-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.106-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.106-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.106-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.106-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.107-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.107-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.107-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.107-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.107-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.108-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.108-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.108-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.108-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.108-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.109-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.109-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.109-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.109-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.109-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.11-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.11-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.11-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.11-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.11-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.110-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.110-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.110-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.110-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.110-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.111-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.111-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.111-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.111-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.111-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.113-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.113-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.113-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.113-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.113-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.114-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.114-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.114-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.114-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.114-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.115-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.115-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.115-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.115-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.115-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.116-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.116-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.116-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.116-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.116-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.117-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.117-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.117-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.117-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.117-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.118-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.118-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.118-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.118-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.118-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.120-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.120-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.120-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.120-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.120-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.121-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.121-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.121-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.121-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.121-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.122-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.122-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.122-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.122-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.122-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.123-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.123-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.123-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.123-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.123-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.124-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.124-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.124-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.124-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.124-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.125-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.125-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.125-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.125-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.125-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.126-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.126-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.126-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.126-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.126-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.129-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.129-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.129-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.129-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.129-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.13-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.13-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.13-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.13-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.13-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.130-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.130-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.130-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.130-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.130-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.131-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.131-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.131-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.131-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.131-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.132-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.132-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.132-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.132-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.132-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.133-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.133-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.133-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.133-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.133-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.134-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.134-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.134-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.134-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.134-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.135-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.135-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.135-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.135-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.135-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.136-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.136-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.136-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.136-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.136-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.137-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.137-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.137-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.137-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.137-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.138-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.138-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.138-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.138-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.138-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.139-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.139-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.139-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.139-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.139-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.140-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.140-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.140-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.140-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.140-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.141-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.141-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.141-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.141-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.141-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.142-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.142-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.142-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.142-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.142-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.143-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.143-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.143-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.143-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.143-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.144-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.144-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.144-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.144-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.144-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.147-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.147-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.147-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.147-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.147-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.148-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.148-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.148-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.148-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.148-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.149-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.149-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.149-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.149-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.149-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.15-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.15-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.15-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.15-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.15-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.150-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.150-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.150-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.150-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.150-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.18-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.18-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.18-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.18-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.18-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.19-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.19-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.19-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.19-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.19-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.20-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.20-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.20-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.20-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.20-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.21-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.21-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.21-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.21-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.21-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.22-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.22-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.22-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.22-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.22-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.23-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.23-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.23-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.23-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.23-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.25-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.25-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.25-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.25-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.25-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.26-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.26-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.26-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.26-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.26-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.29-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.29-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.29-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.29-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.29-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.3-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.3-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.3-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.3-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.3-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.30-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.30-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.30-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.30-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.30-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.31-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.31-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.31-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.31-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.31-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.34-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.34-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.34-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.34-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.34-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.35-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.35-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.35-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.35-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.35-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.36-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.36-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.36-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.36-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.36-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.38-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.38-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.38-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.38-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.38-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.4-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.4-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.4-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.4-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.4-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.41-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.41-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.41-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.41-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.41-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.42-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.42-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.42-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.42-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.42-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.45-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.45-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.45-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.45-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.45-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.47-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.47-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.47-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.47-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.47-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.49-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.49-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.49-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.49-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.49-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.5-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.5-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.5-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.5-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.5-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.50-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.50-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.50-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.50-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.50-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.52-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.52-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.52-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.52-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.52-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.55-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.55-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.55-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.55-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.55-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.56-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.56-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.56-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.56-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.56-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.57-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.57-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.57-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.57-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.57-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.58-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.58-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.58-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.58-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.58-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.61-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.61-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.61-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.61-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.61-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.62-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.62-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.62-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.62-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.62-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.63-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.63-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.63-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.63-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.63-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.65-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.65-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.65-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.65-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.65-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.67-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.67-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.67-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.67-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.67-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.68-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.68-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.68-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.68-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.68-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.7-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.7-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.7-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.7-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.7-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.72-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.72-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.72-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.72-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.72-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.73-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.73-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.73-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.73-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.73-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.78-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.78-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.78-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.78-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.78-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.79-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.79-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.79-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.79-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.79-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.8-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.8-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.8-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.8-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.8-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.80-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.80-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.80-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.80-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.80-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.81-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.81-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.81-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.81-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.81-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.84-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.84-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.84-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.84-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.84-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SC16.88-DL1 [4]
SG2000 derivative PBD 1
Microtubule (MT)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.88-DL2 [4]
SG3312
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
SC16.88-DL3 [4]
SG2000 derivative PBD 3
Human Deoxyribonucleic acid (hDNA)
Mal-PEG8-Val-Ala
 ADC Info 
SC16.88-DL4 [4]
SG2219
Human Deoxyribonucleic acid (hDNA)
Iodoacetamide-PEG4-Val-Ala-PABC
 ADC Info 
SC16.88-DL5 [4]
SG3199
Human Deoxyribonucleic acid (hDNA)
Mc-PEG8-Val-Ala-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
SHR-4849
SHR9265
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
SYM004 (anti-DLL3)
 Antibody Info 
ADC Name Payload Target Linker ADC Info
WO2024169913A1 ADC04-01-8 [5]
B19
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)
Mc-Val-Cit-PABC
 ADC Info 
WO2024169913A1 ADC04-02-8 [5]
B19
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)
Mc-Val-Cit-PABC
 ADC Info 
WO2024169913A1 ADC04-06-8 [5]
B19
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)
Mc-Val-Ala-PABC
 ADC Info 
WO2024169913A1 ADC04-06-4 [5]
B63
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)
Mc-Val-Ala-PABC
 ADC Info 
WO2024169913A1 ADC04-07-8 [5]
B63
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)
Mc-Val-Ala-PABC
 ADC Info 
WO2024169913A1 ADC04-07-4 [5]
B19
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)
(Linker-02)MC-PEG-VA-PAB
 ADC Info 
WO2024169913A1 ADC04-08-8 [5]
B19
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)
(Linker-02)MC-PEG-VA-PAB
 ADC Info 
WO2024169913A1 ADC04-08-4 [5]
B19
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)
(Linker-03)SMCC-TAZ-PEG-VC-PAB
 ADC Info 
WO2024169913A1 ADC04-09-8 [5]
Smol006
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)
Mc-Val-Cit-PABC
 ADC Info 
WO2024169913A1 ADC04-09-4 [5]
Smol006
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)
Mc-Val-Cit-PABC
 ADC Info 
Zocilurtatug
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Zocilurtatug pelitecan [6]
YL0010014
DNA topoisomerase 1 (TOP1)
VK*G-NHCH2-O linker
 ADC Info 
Undisclosed
 Antibody Info 
ADC Name Payload Target Linker ADC Info
ZL-1310 [7]
YL0010014
DNA topoisomerase I (TOP1)
Tumor microenviroment activable tripeptide linker
 ADC Info 
Anti-DLL3 ADC (IntoCell/Y-Biologics) [8]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
PLB-001 [9]
Exatecan
DNA topoisomerase 1 (TOP1)
Undisclosed
 ADC Info 
WO2024043319A1 80 [10]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
CN119630431A ADC-92 [11]
CN119630431A-ADC-82-PAYLOAD
Undisclosed
CN119630431A-ADC-82-LINKER
 ADC Info 
References
Ref 1 Pharmaceuticals containing antibody-drug complexes containing hemiasterin derivatives
Ref 2 Biokin pharma Prospectus; 2022
Ref 3 Antibody-drug complexes containing hemiasterlin derivatives
Ref 4 Novel antibody conjugates and uses thereof; 2014-08-28.
Ref 5 Domide molecular glue derivative and use thereof
Ref 6 Zai lab announces strategic partnership and global license agreement with medilink therapeutics for a next generation antibody-drug conjugate program in oncology
Ref 7 A Study of ZL-1310 in Subjects With Small Cell Lung Cancer
Ref 8 Introduction to basic information on anti-DLL3 ADC (IntoCell/Y-Biologics).
Ref 9 PLB-001, a novel anti-dll3 ADC with topoisomerase 1 inhibitor-based linker-payload for treatment of SCLC
Ref 10 Antibody-drug complexes
Ref 11 Antibody-drug conjugates