General Information of This Antibody-drug Conjugate (ID: DRG0UYIOG)
ADC Name
Zocilurtatug pelitecan
Synonyms
zocilurtatug pelitecan; YL212; ZL-1310; zoci
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Organization
MediLink Therapeutics (Originator);Zai Lab
Drug Status
Phase 3
Drug-to-Antibody Ratio
8
Structure
Antibody Name
Zocilurtatug
 Antibody Info 
Antigen Name
Delta-like protein 3 (DLL3)
 Antigen Info 
Payload Name
YL0010014
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
VK*G-NHCH2-O linker
 Linker Info 
Conjugate Type
Random Cysteines
Combination Type
pelitecan
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Lung cancer
1 Trials
Clinical trial identifier
NCT07218146; jRCT2031250762; CTR20260381
Unspecific solid tumor
1 Trials
Clinical trial identifier
NCT06885281; CTR20251434