Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0ZUAIJ
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| ADC Name |
OncoFAP-GlyPro-Dxd
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| Synonyms |
OncoFAP-GlyPro-Dxd
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| Organization |
Philochem AG; Swiss Federal Institute of Technology; Philogen S.p.A.
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| Drug Status |
Investigative
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| Structure |
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| Antibody Name |
OncoFAP
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Antibody Info | ||||
| Antigen Name |
Prolyl endopeptidase FAP (FAP)
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Antigen Info | ||||
| Payload Name |
DX-8951 derivative (DXd)
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Maleimido Caproyl-GlyPro-PAB linker
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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