Linker Information
General Information of This Linker
| Linker ID |
LIN0KHGRP
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| Linker Name |
Maleimido Caproyl-GlyPro-PAB linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C24H30N4O6
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| Isosmiles |
O=C(N1CCCCCC(NCC(N2CCC[C@H]2C(NC3=CC=C(CO)C=C3)=O)=O)=O)C=CC1=O
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| PubChem CID | ||||||
| InChI |
InChI=1S/C24H30N4O6/c29-16-17-7-9-18(10-8-17)26-24(34)19-5-4-14-27(19)23(33)15-25-20(30)6-2-1-3-13-28-21(31)11-12-22(28)32/h7-12,19,29H,1-6,13-16H2,(H,25,30)(H,26,34)/t19-/m0/s1
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| InChIKey |
VMXNGZATTUKEQS-IBGZPJMESA-N
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| Pharmaceutical Properties |
Molecule Weight
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470.526
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Polar area
|
136.12
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Complexity
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901.2899266
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xlogp Value
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0.71
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Heavy Count
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34
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Rot Bonds
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11
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Hbond acc
|
6
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Hbond Donor
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3
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Each Antibody-drug Conjugate Related to This Linker