Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0ZTCHE
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| ADC Name |
anti-HER-MC-VC-FABC-MMAE
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| Synonyms |
Anti-HER-MC-VC-FABC-MMAE
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| Organization |
GENZYME CORPORATION
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
3.8
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| Structure |
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| Antibody Name |
Anti-Her2 WT
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Aminooxy-Cys linker
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
Aminooxy-Cys-MC-VC-FABC-MMAE
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