Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0ZROBT
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ADC Name |
CD19-ATAC
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Synonyms |
CD19ATAC; CD19 ATAC
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Organization |
Heidelberg Pharma AG
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Drug Status |
Clinical candidate
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Indication |
In total 1 Indication(s)
Hematologic cancer [ICD11:2B3Z]
Clinical candidate
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Drug-to-Antibody Ratio |
2
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Structure | ||||||
Antibody Name |
Undisclosed
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Antigen Name |
B-lymphocyte antigen CD19 (CD19)
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Antigen Info | ||||
Payload Name |
HDP 30.2115
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Payload Info | ||||
Therapeutic Target |
DNA-directed RNA polymerase II subunit RPB2 (POLR2B); DNA-directed RNA polymerase III subunit RPC7 (POLR3G)
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Target Info | ||||
Linker Name |
Mal-Val-Ala-PAB
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Linker Info | ||||
Conjugate Type |
Site-specific conjugation through the engineered cysteine (THIOMAB).
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