Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0ZRFXI
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| ADC Name |
Site-sepcific ADC 12
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| Synonyms |
Site-sepcific ADC 12
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| Organization |
Shanghai Institute of Materia Medica, Chinese Academy of Sciences.; University of Chinese Academy of Sciences.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
2
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| Structure |
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| Antibody Name |
Zilovertamab
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Antibody Info | ||||
| Antigen Name |
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
TE-VC-PAB
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Linker Info | ||||
| Conjugate Type |
Direct preparation of site-specific ADC with unpurified antibodies in culture medium.
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