Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0ZMQMZ
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| ADC Name |
Anti-endosialin-Mc-Val-Cit-PABC-MMAE
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| Synonyms |
Anti endosialin MC VC PABC MMAE
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| Organization |
Genzyme Corp.
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| Drug Status |
Clinical candidate
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| Indication |
In total 2 Indication(s)
Ewing sarcoma [ICD11:2B52]
Clinical candidate
Neuroblastoma [ICD11:2A00]
Clinical candidate
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| Drug-to-Antibody Ratio |
3-4
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| Structure |
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| Antibody Name |
Undisclosed
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| Antigen Name |
Endosialin (CD248)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
Vedotin
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