Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ID: DRG0ZBCCA)
| ADC Name |
MGC028
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| Synonyms |
MGC028
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| Organization |
MacroGenics (Originator)
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| Drug Status |
Phase 1
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| Drug-to-Antibody Ratio |
4
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| Structure |
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| Antibody Name |
Anti-ADAM9 antibody
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Antibody Info | ||||
| Antigen Name |
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)
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Antigen Info | ||||
| Payload Name |
Exatecan
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Payload Info | ||||
| Payload Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Bicyclononyne carbamoyl sulfamide Val-Ala-PABC
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Linker Info | ||||
| Conjugate Type |
Enzymatic Catalysis
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2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
| Indication | Phase 1 | Phase 2 | Phase 3 | Approved | ||
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| Colorectal cancer |
1 Trials
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| Pancreatic cancer |
1 Trials
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| Biliary tract cancer |
1 Trials
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| Lung cancer |
1 Trials
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