General Information of This Antibody-drug Conjugate (ID: DRG0ZAECD)
ADC Name
AGS-16M8F
Synonyms
AGS-16M8F
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Organization
Agensys (Top20 MNC) (Originator)
Drug Status
Phase 1 (discontinued)
Drug-to-Antibody Ratio
~4
Structure
Antibody Name
Anti-ENPP3 antibody
 Antibody Info 
Antigen Name
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3)
 Antigen Info 
Payload Name
Monomethyl auristatin F
 Payload Info 
Payload Target
Microtubule (MT)
 Target Info 
Linker Name
Maleimido-caproyl
 Linker Info 
Conjugate Type
Random Cysteines
Combination Type
mafodotin
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Kidney cancer
1 Trials
Trial ID
NCT01114230