Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0YMHFB
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| ADC Name |
DAR8-alphaCD30-mDPR-Gluc-MMAE
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| Synonyms |
DAR8 alphaCD30 mDPR gluc MMAE
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| Organization |
Seagen Inc.
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| Drug Status |
Clinical candidate
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| Indication |
In total 1 Indication(s)
Hodgkin lymphoma [ICD11:2B30]
Clinical candidate
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| Drug-to-Antibody Ratio |
8
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| Structure |
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| Antibody Name |
Anti-CD30 DAR8-alphaCD30-mDPR-gluc-MMAE mAb
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Antibody Info | ||||
| Antigen Name |
Tumor necrosis factor receptor superfamily member 8 (TNFRSF8)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Quaternary ammonium linker Gluc
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
Gluc-MMAE
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