Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0YIRWI
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| ADC Name |
Anti-N3-vc0101
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| Synonyms |
Anti-N3 ADC
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| Drug Status |
Investigative
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| Indication |
In total 2 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Investigative
Lung cancer [ICD11:2C25]
Investigative
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| Drug-to-Antibody Ratio |
3.9
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| Structure |
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| Antibody Name |
Anti-NOTCH3 mAb
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Antibody Info | ||||
| Antigen Name |
Neurogenic locus notch homolog protein 3 (NOTCH3)
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Antigen Info | ||||
| Payload Name |
Auristatin 0101
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Site-specific conjugated of maleimidocaproyl with cysteine free thiol via Michael addition.
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| Combination Type |
Pelidotin
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