Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0XUBIO
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| ADC Name |
TWI852077B-J14
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| Synonyms |
J14
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| Organization |
NOVARTIS AG
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
4
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| Structure |
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| Antibody Name |
Anti-cKIT Fab'1
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Antibody Info | ||||
| Antigen Name |
Mast/stem cell growth factor receptor Kit (KIT)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin F
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random conjugation through nucleophilic lysines
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| Combination Type |
Mc-MMAF
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