General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0XPPOZ
ADC Name
Vorsetuzumab mafodotin
Synonyms
SGN 75; SGN-75; SGN75; Vorsetuzumab mafodotin
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Organization
Seagen Inc.
Drug Status
Phase 1 (Terminated)
Indication
In total 2 Indication(s)
Kidney cancer
Phase 1
Clinical Trial
Unspecific non-hodgkin lymphoma
Phase 1
Clinical Trial
Drug-to-Antibody Ratio
3 to 4
Structure
Antibody Name
Vorsetuzumab
 Antibody Info 
Antigen Name
CD70 antigen (CD70)
 Antigen Info 
Payload Name
Monomethyl auristatin F
 Payload Info 
Therapeutic Target
Microtubule (MT)
 Target Info 
Linker Name
Maleimido-caproyl
 Linker Info 
Conjugate Type
Random Cysteines
Combination Type
mafodotin
Puchem SID
472405492 , 172650770 , 319417830 , 404772780 , 160676989 , 172232435 , 476262676 , 476269266
Drugbank ID
DB15352
DrugMap ID
DMATEL0
TTD ID
D08WTE
ChEBI ID
CHEMBL2108672