Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0XKZBM
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| ADC Name |
CD70-MMAF-ADC
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| Synonyms |
CD70 MMAF ADC
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| Drug Status |
Investigative
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| Indication |
In total 3 Indication(s)
Non Hodgkin lymphoma [ICD11:2B33]
Investigative
Ovarian cancer [ICD11:2C73]
Investigative
Renal cell carcinoma [ICD11:2C90]
Investigative
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| Drug-to-Antibody Ratio |
3
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| Structure |
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| Antibody Name |
Vorsetuzumab
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Antibody Info | ||||
| Antigen Name |
CD70 antigen (CD70)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin F
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Maleimido-caproyl
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Linker Info | ||||
| Conjugate Type |
Inter-chain cysteine.
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| Combination Type |
McMMAF
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