Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0XHBEF
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ADC Name |
SG1-Val-Cit-MMAF8
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Synonyms |
SG1 vcMMAF8
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Organization |
Seagen Inc.
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Drug Status |
Clinical candidate
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Indication |
In total 1 Indication(s)
Multiple myeloma [ICD11:2A83]
Clinical candidate
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Structure | ||||||
Antibody Name |
SG1
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Antibody Info | ||||
Antigen Name |
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17)
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Antigen Info | ||||
Payload Name |
Monomethyl auristatin F
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Payload Info | ||||
Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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Combination Type |
VcMMAF
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