Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0WYCOU
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|---|---|---|---|---|---|---|
| ADC Name |
EV20/MMAF
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| Synonyms |
EV20-MMAF; EV20 MMAF; EV20MMAF
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| Organization |
MediaPharma Srl
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| Drug Status |
Clinical candidate
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| Indication |
In total 2 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Clinical candidate
Skin cancer [ICD11:2C30-2C37]
Clinical candidate
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| Drug-to-Antibody Ratio |
4.7-5
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| Structure |
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| Antibody Name |
EV20
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-3 (ERBB3)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin F
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Maleimido-caproyl
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Linker Info | ||||
| Conjugate Type |
Inter-chain cysteine.
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| Combination Type |
Mafodotin
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