Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0WMSEQ
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| ADC Name |
Her2-Saci- (mc-MMAF)- (mc-A6)
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| Synonyms |
ADC635
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| Organization |
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
2.4-6.5
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| Antibody Name |
Sacituzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin F
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Conjugate Type |
Random conjugation through nucleophilic lysines
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