Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ID: DRG0VQRJE)
| ADC Name |
WO2024231224A2 ADC-AFI-DXd
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| Synonyms |
ADC-AFI-DXd
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| Organization |
BIONTECH SE
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
4.0۪.4
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| Structure |
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| Antibody Name |
mAb_v64
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Antibody Info | ||||
| Antigen Name |
Tumor-associated carbohydrate antigen sialyl-Tn (STn)
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Antigen Info | ||||
| Payload Name |
DX-8951 derivative (DXd)
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Payload Info | ||||
| Payload Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Mc-Gly-Gly-Phe-Gly
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines
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