Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0VPODR
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ADC Name |
Alemtuzumab-Compound 36
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Synonyms |
Alemtuzumab Compound 36
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Organization |
Rongchang Pharmaceuticals Ltd.
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Drug Status |
Investigative
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Indication |
In total 1 Indication(s)
Chronic lymphocytic leukemia [ICD11:2A82]
Investigative
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Drug-to-Antibody Ratio |
3.5-4
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Antibody Name |
Alemtuzumab
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Antibody Info | ||||
Antigen Name |
CAMPATH-1 antigen (CD52)
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Antigen Info | ||||
Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
Linker Name |
Alemtuzumab-Compound 36 linker
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Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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