Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0UWGBV
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| ADC Name |
39757732 ADC4
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| Synonyms |
ADC4
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| Organization |
Chinese Academy of Medical Sciences.; Peking Union Medical College.; Shanghai Institute of Materia Medica, Chinese Academy of Sciences.; University of Chinese Academy of Sciences.; Lingang Laboratory.; ShanghaiTech University.; Nanjing University of Chinese Medicine.; Shenyang Pharmaceutical University.; Hangzhou Institute of Advanced Study.; Shanghai GlycanLink Biotech. Co. Ltd.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
2
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| Structure |
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| Antibody Name |
Ab-2
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Antibody Info | Antigen Name |
Undisclosed
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| Payload Name |
DX-8951 derivative (DXd)
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
D4 Linker
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Linker Info | ||||
| Conjugate Type |
Glycosite-specific conjugation.
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