General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0TOMLD
ADC Name
GB7008-01-Val-Cit-MMAE
Synonyms
Anti-CLDN6 antibody drug conjugate (cancer); GB-7008-01 vcMMAE
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Organization
Shanghai Genechem Co., Ltd.
Drug Status
Investigative
Indication
In total 1 Indication(s)
Ovarian cancer
Clinical candidate
.
Drug-to-Antibody Ratio
4
Structure
Antibody Name
GB7008-01
 Antibody Info 
Antigen Name
Claudin-6 (CLDN6)
 Antigen Info 
Payload Name
Monomethyl auristatin E
 Payload Info 
Therapeutic Target
Microtubule (MT)
 Target Info 
Linker Name
Mc-Val-Cit-PABC
 Linker Info 
Conjugate Type
Random conjugation through reduced inter-chain cysteines.
Combination Type
Vedotin