Antigen ID	TAR0UDQEU
Antigen Name	Claudin-6 (CLDN6)
Gene Name	CLDN6
Gene ID	9074
Synonym	Skullin
Sequence	MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV     Click to Show/Hide
Family	Chondroitin N-acetylgalactosaminyltransferase family
Function	Plays a major role in tight junction-specific obliteration of the intercellular space.     Click to Show/Hide
Uniprot Entry	CLD6_HUMAN
HGNC ID	HGNC:2048
KEGG ID	hsa:9074

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	GB7008-01-Val-Cit-MMAE	Monomethyl auristatin E	Microtubule (MT)	Mc-Val-Cit-PABC	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	IMAB027-Val-Cit-MMAE	Monomethyl auristatin E	Microtubule (MT)	Mc-Val-Cit-PABC	[2]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	DS-9606	Undisclosed	Undisclosed	Undisclosed	[3]
ADC Info	TORL-1-23	Undisclosed	Undisclosed	Undisclosed	[4]

Differential expression pattern of antigen in diseases
The Studied Tissue	Gingival
The Specific Disease	Bacterial infection of gingival
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.535469148; Fold-change: 0.008010017; Z-score: 0.047500327
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Differential expression pattern of antigen in diseases
The Studied Tissue	Brainstem
The Specific Disease	Glioma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.771146472; Fold-change: -0.062215004; Z-score: -0.511442906
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The Studied Tissue	White matter
The Specific Disease	Glioma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.01692224; Fold-change: 0.204771301; Z-score: 0.616035229
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The Studied Tissue	Brainstem
The Specific Disease	Neuroectodermal tumor
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 6.28E-05; Fold-change: -0.699214949; Z-score: -2.166550138
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The Studied Tissue	Nervous
The Specific Disease	Brain cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.30E-77; Fold-change: -0.374659653; Z-score: -1.458042308
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Polycythemia vera
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 4.26E-09; Fold-change: 0.247718509; Z-score: 1.265983187
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The Studied Tissue	Whole blood
The Specific Disease	Myelofibrosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.100865813; Fold-change: 0.111426193; Z-score: 0.582869355
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Myelodysplastic syndromes
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.445794882; Fold-change: 0.024038372; Z-score: 0.189857924
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.584671398; Fold-change: -0.005973087; Z-score: -0.064514615
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Tonsil
The Specific Disease	Lymphoma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.522117379; Fold-change: -0.090176457; Z-score: -0.655707765
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Differential expression pattern of antigen in diseases
The Studied Tissue	Gastric
The Specific Disease	Gastric cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.135275136; Fold-change: -0.446047092; Z-score: -1.688787265
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.163771592; Fold-change: -0.102539547; Z-score: -0.358079842
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Colon
The Specific Disease	Colon cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 2.52E-09; Fold-change: -0.129542642; Z-score: -0.557810521
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 5.88E-09; Fold-change: -0.126954014; Z-score: -0.586376721
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Pancreas
The Specific Disease	Pancreatic cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.001661468; Fold-change: -0.27092822; Z-score: -0.949144584
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 9.86E-08; Fold-change: -0.297677159; Z-score: -0.837145258
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Differential expression pattern of antigen in diseases
The Studied Tissue	Liver
The Specific Disease	Liver cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 2.00E-09; Fold-change: -0.261572336; Z-score: -1.238560261
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 2.94E-12; Fold-change: -0.174827903; Z-score: -0.854132995
The Expression Level of Disease Section Compare with the Other Disease Section	p-value: 0.054357396; Fold-change: -0.386166049; Z-score: -1.659562708
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Differential expression pattern of antigen in diseases
The Studied Tissue	Lung
The Specific Disease	Lung cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 4.15E-08; Fold-change: 0.006677049; Z-score: 0.033167095
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 5.48E-12; Fold-change: 0.024431944; Z-score: 0.12842937
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Melanoma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.92703615; Fold-change: 0.1426334; Z-score: 0.266748065
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Differential expression pattern of antigen in diseases
The Studied Tissue	Muscle
The Specific Disease	Sarcoma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 8.24E-133; Fold-change: -0.455319247; Z-score: -1.625801941
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.001101795; Fold-change: -0.814065608; Z-score: -5.891727282
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Differential expression pattern of antigen in diseases
The Studied Tissue	Breast
The Specific Disease	Breast cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.313840982; Fold-change: -0.011829207; Z-score: -0.0493229
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.585067491; Fold-change: -0.046817371; Z-score: -0.180798795
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Ovarian
The Specific Disease	Ovarian cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 9.56E-06; Fold-change: 0.178807594; Z-score: 0.678189314
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 1.50E-26; Fold-change: 0.383883313; Z-score: 2.774622355
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Cervical
The Specific Disease	Cervical cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.067385527; Fold-change: -0.065785858; Z-score: -0.342477982
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Differential expression pattern of antigen in diseases
The Studied Tissue	Endometrium
The Specific Disease	Uterine cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.000949945; Fold-change: 0.107886005; Z-score: 0.303737485
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.161103134; Fold-change: -0.388954019; Z-score: -1.525522303
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Differential expression pattern of antigen in diseases
The Studied Tissue	Prostate
The Specific Disease	Prostate cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.004229643; Fold-change: -0.687823365; Z-score: -1.475947775
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bladder
The Specific Disease	Bladder cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.192433494; Fold-change: 0.057100568; Z-score: 0.396673577
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Differential expression pattern of antigen in diseases
The Studied Tissue	Uvea
The Specific Disease	Retinoblastoma tumor
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.022546246; Fold-change: -0.192857771; Z-score: -1.882853855
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Differential expression pattern of antigen in diseases
The Studied Tissue	Thyroid
The Specific Disease	Thyroid cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 2.02E-05; Fold-change: 0.090999964; Z-score: 0.586346913
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 6.89E-07; Fold-change: 0.122075077; Z-score: 1.020541921
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Adrenal cortex
The Specific Disease	Adrenocortical carcinoma
The Expression Level of Disease Section Compare with the Other Disease Section	p-value: 0.123925797; Fold-change: -0.107002403; Z-score: -0.740439178
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Differential expression pattern of antigen in diseases
The Studied Tissue	Head and neck
The Specific Disease	Head and neck cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.860046522; Fold-change: 0.007080374; Z-score: 0.046700263
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Differential expression pattern of antigen in diseases
The Studied Tissue	Pituitary
The Specific Disease	Pituitary gonadotrope tumor
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.012804493; Fold-change: 0.337496749; Z-score: 1.519092045
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The Studied Tissue	Pituitary
The Specific Disease	Pituitary cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.00040118; Fold-change: 0.311426397; Z-score: 1.579657089
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Thrombocytopenia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.46369136; Fold-change: -0.015401757; Z-score: -0.062882061
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Lupus erythematosus
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.047787436; Fold-change: -0.082133584; Z-score: -0.173077753
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral monocyte
The Specific Disease	Autoimmune uveitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.000475711; Fold-change: -0.202053601; Z-score: -1.79283829
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Familial hypercholesterolemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.051073564; Fold-change: -0.12376507; Z-score: -0.466348208
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Differential expression pattern of antigen in diseases
The Studied Tissue	Superior temporal cortex
The Specific Disease	Schizophrenia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.944403449; Fold-change: 0.093819524; Z-score: 0.940634848
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Differential expression pattern of antigen in diseases
The Studied Tissue	Spinal cord
The Specific Disease	Multiple sclerosis
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.256405755; Fold-change: -0.078591762; Z-score: -0.576977535
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The Studied Tissue	Plasmacytoid dendritic cells
The Specific Disease	Multiple sclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.150257005; Fold-change: 0.083471491; Z-score: 0.293011322
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peritumoral cortex
The Specific Disease	Epilepsy
The Expression Level of Disease Section Compare with the Other Disease Section	p-value: 0.432260516; Fold-change: 0.383756872; Z-score: 1.434607214
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Cardioembolic Stroke
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.089599969; Fold-change: 0.040615996; Z-score: 0.352554964
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The Studied Tissue	Peripheral blood
The Specific Disease	Ischemic stroke
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.201505098; Fold-change: 0.075907573; Z-score: 0.660225566
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Differential expression pattern of antigen in diseases
The Studied Tissue	White matter
The Specific Disease	HIV
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.147300158; Fold-change: -0.051628184; Z-score: -0.201605313
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Influenza
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.003512704; Fold-change: 0.585230216; Z-score: 21.73561654
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Chronic hepatitis C
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.812778604; Fold-change: -0.002406619; Z-score: -0.037713231
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Sepsis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.630235524; Fold-change: 0.027079819; Z-score: 0.089629103
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Septic shock
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.606520609; Fold-change: 0.022467515; Z-score: 0.067439445
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Pediatric respiratory syncytial virus infection
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.355616905; Fold-change: 0.013902643; Z-score: 0.135604503
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Essential hypertension
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.556304439; Fold-change: 0.193162317; Z-score: 9.136612555
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Myocardial infarction
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.864905028; Fold-change: -0.065915022; Z-score: -0.119405824
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Coronary artery disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.230791059; Fold-change: -0.136074224; Z-score: -0.764602935
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Differential expression pattern of antigen in diseases
The Studied Tissue	Calcified aortic valve
The Specific Disease	Aortic stenosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.192877384; Fold-change: 0.090184117; Z-score: 0.501213774
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Arteriosclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.354978232; Fold-change: 0.035076986; Z-score: 0.277474792
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Differential expression pattern of antigen in diseases
The Studied Tissue	Intracranial artery
The Specific Disease	Aneurysm
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.745904825; Fold-change: 0.002520358; Z-score: 0.010659496
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Immunodeficiency
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.348056051; Fold-change: -0.000937944; Z-score: -0.01105
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Differential expression pattern of antigen in diseases
The Studied Tissue	Hyperplastic tonsil
The Specific Disease	Apnea
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.021852328; Fold-change: -0.220680192; Z-score: -2.079880576
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Olive pollen allergy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.052855281; Fold-change: 0.160552626; Z-score: 1.707152208
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Differential expression pattern of antigen in diseases
The Studied Tissue	Sinus mucosa
The Specific Disease	Chronic rhinosinusitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.659619035; Fold-change: 0.013506314; Z-score: 0.189927548
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Differential expression pattern of antigen in diseases
The Studied Tissue	Lung
The Specific Disease	Chronic obstructive pulmonary disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.800754429; Fold-change: -0.01890475; Z-score: -0.118166954
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The Studied Tissue	Small airway epithelium
The Specific Disease	Chronic obstructive pulmonary disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 7.52E-05; Fold-change: 0.214377177; Z-score: 0.993913207
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Differential expression pattern of antigen in diseases
The Studied Tissue	Nasal and bronchial airway
The Specific Disease	Asthma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.174995681; Fold-change: -0.068791223; Z-score: -0.271271316
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Differential expression pattern of antigen in diseases
The Studied Tissue	Nasal Epithelium
The Specific Disease	Human rhinovirus infection
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.818681947; Fold-change: -0.004600224; Z-score: -0.043737925
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Differential expression pattern of antigen in diseases
The Studied Tissue	Lung
The Specific Disease	Idiopathic pulmonary fibrosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.572826678; Fold-change: -0.105805795; Z-score: -0.727490464
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Differential expression pattern of antigen in diseases
The Studied Tissue	Gingival
The Specific Disease	Periodontal disease
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.007933449; Fold-change: 0.0391972; Z-score: 0.263104673
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Differential expression pattern of antigen in diseases
The Studied Tissue	Gastric antrum
The Specific Disease	Eosinophilic gastritis
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.126222564; Fold-change: 0.168308781; Z-score: 1.487892794
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Differential expression pattern of antigen in diseases
The Studied Tissue	Liver
The Specific Disease	Liver failure
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.011553641; Fold-change: -0.306609577; Z-score: -1.257457714
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Differential expression pattern of antigen in diseases
The Studied Tissue	Colon mucosal
The Specific Disease	Ulcerative colitis
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.177301309; Fold-change: -0.129810021; Z-score: -0.459529127
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Differential expression pattern of antigen in diseases
The Studied Tissue	Rectal colon
The Specific Disease	Irritable bowel syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.590295801; Fold-change: 0.007303706; Z-score: 0.039770679
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Atopic dermatitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.019269191; Fold-change: 0.01393867; Z-score: 0.169169484
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Psoriasis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 2.33E-08; Fold-change: -0.157571682; Z-score: -0.539239455
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 4.10E-49; Fold-change: 0.906265742; Z-score: 5.233458705
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Vitiligo
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.202850253; Fold-change: -0.106474336; Z-score: -0.745217636
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin from scalp
The Specific Disease	Alopecia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.555830138; Fold-change: -0.032767933; Z-score: -0.160252173
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Sensitive skin
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.366829611; Fold-change: 0.057054075; Z-score: 0.456611683
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Differential expression pattern of antigen in diseases
The Studied Tissue	Synovial
The Specific Disease	Osteoarthritis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.129952059; Fold-change: -0.135225679; Z-score: -0.367523394
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Arthropathy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.949863901; Fold-change: 0.036121049; Z-score: 0.479145118
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Arthritis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.002505414; Fold-change: 0.090438423; Z-score: 0.36452676
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Differential expression pattern of antigen in diseases
The Studied Tissue	Synovial
The Specific Disease	Rheumatoid arthritis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.000924343; Fold-change: -0.540787151; Z-score: -2.311986528
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Differential expression pattern of antigen in diseases
The Studied Tissue	Pheripheral blood
The Specific Disease	Ankylosing spondylitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.285579582; Fold-change: 0.001593381; Z-score: 0.013945739
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Osteoporosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.022635687; Fold-change: 0.249191224; Z-score: 2.448548239
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Differential expression pattern of antigen in diseases
The Studied Tissue	Endometrium
The Specific Disease	Endometriosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.428246129; Fold-change: -0.042678633; Z-score: -0.152311169
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bladder
The Specific Disease	Interstitial cystitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.239572096; Fold-change: 0.009107347; Z-score: 0.080440842
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Differential expression pattern of antigen in diseases
The Studied Tissue	Myometrium
The Specific Disease	Preterm birth
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.085394979; Fold-change: -0.113121034; Z-score: -1.185573123
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Acute myelocytic leukemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.095730229; Fold-change: 0.050897751; Z-score: 0.243207978
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Myeloma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.001954348; Fold-change: 0.196366464; Z-score: 1.49989417
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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The Studied Tissue	Peripheral blood
The Specific Disease	Myeloma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.924851013; Fold-change: -0.040882882; Z-score: -0.358495438
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Oral
The Specific Disease	Oral cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 6.81E-07; Fold-change: -0.380048207; Z-score: -1.425055789
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.484067836; Fold-change: 0.03829152; Z-score: 0.17963795
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Esophagus
The Specific Disease	Esophagal cancer
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.415762401; Fold-change: -0.067219523; Z-score: -0.486896527
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Rectal colon
The Specific Disease	Rectal cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.919717049; Fold-change: 0.044129631; Z-score: 0.237033264
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.024548091; Fold-change: -0.195587375; Z-score: -1.198853435
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Skin cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.10E-06; Fold-change: -0.297829572; Z-score: -0.659375324
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 5.65E-43; Fold-change: 0.614132316; Z-score: 1.920950742
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Kidney
The Specific Disease	Renal cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.00039256; Fold-change: -0.549381218; Z-score: -1.394865353
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 7.75E-26; Fold-change: -0.659459851; Z-score: -2.045934447
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Urothelium
The Specific Disease	Ureter cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.697948854; Fold-change: 0.022042003; Z-score: 0.103784686
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Adipose
The Specific Disease	Simpson golabi behmel syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.793137893; Fold-change: -0.007140794; Z-score: -0.045883298
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Differential expression pattern of antigen in diseases
The Studied Tissue	Perituberal
The Specific Disease	Tuberous sclerosis complex
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.663701902; Fold-change: 0.020220401; Z-score: 0.16112737
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Anemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.225734604; Fold-change: 0.194817836; Z-score: 0.955886898
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Sickle cell disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.305760726; Fold-change: 0.171037284; Z-score: 0.578243557
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Thrombocythemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.00379778; Fold-change: 0.205837533; Z-score: 1.087689753
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Scleroderma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.955341503; Fold-change: 0.00934056; Z-score: 0.074678995
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Differential expression pattern of antigen in diseases
The Studied Tissue	Salivary gland
The Specific Disease	Sjogren syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.96115092; Fold-change: 0.093068549; Z-score: 0.417198818
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.007409732; Fold-change: -0.401553763; Z-score: -1.930579973
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Behcet disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.389153682; Fold-change: -0.053806118; Z-score: -0.345909062
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Autosomal dominant monocytopenia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.032002167; Fold-change: -0.082636724; Z-score: -0.74283207
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Liver
The Specific Disease	Type 2 diabetes
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.789084899; Fold-change: -0.027589489; Z-score: -0.23219004
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Vastus lateralis muscle
The Specific Disease	Polycystic ovary syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.338436043; Fold-change: 0.014504281; Z-score: 0.13246948
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Subcutaneous Adipose
The Specific Disease	Obesity
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.170397719; Fold-change: -0.051616791; Z-score: -0.383103408
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Biceps muscle
The Specific Disease	Pompe disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.380419828; Fold-change: -0.050675821; Z-score: -0.325772398
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Batten disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.970714874; Fold-change: -0.026709741; Z-score: -0.354844637
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Autism
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.660294333; Fold-change: 0.090470643; Z-score: 0.387216726
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Anxiety disorder
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.406988384; Fold-change: 0.007004583; Z-score: 0.035309178
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Substantia nigra
The Specific Disease	Parkinson disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.641428216; Fold-change: 0.016915473; Z-score: 0.07947899
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Huntington disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.607294423; Fold-change: -0.025486366; Z-score: -0.146817077
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Entorhinal cortex
The Specific Disease	Alzheimer disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.994393726; Fold-change: -0.024238553; Z-score: -0.172104472
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Seizure
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.464710859; Fold-change: -0.150866188; Z-score: -0.60750036
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Lateral sclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.493466853; Fold-change: 0.088947234; Z-score: 0.887486799
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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The Studied Tissue	Cervical spinal cord
The Specific Disease	Lateral sclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.220261252; Fold-change: -0.012759595; Z-score: -0.075347373
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Muscle
The Specific Disease	Muscular atrophy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 8.59E-05; Fold-change: -0.344870508; Z-score: -1.736494092
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Muscle
The Specific Disease	Myopathy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.014010569; Fold-change: -0.373825863; Z-score: -1.868662536
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Ref 1	Introduction to basic information on ADC drug GB-7008-01-vcMMAE.
Ref 2	Preclinical characterization of the safety and antitumor activity of IMAB027-vcMMAE, an anticlaudin 6 antibody-drug conjugate. Cancer Res (2018) 78 (13_Supplement): 1778.
Ref 3	A Study of DS-9606a in Patients With Advanced Solid Tumors; NCT05394675.
Ref 4	TORL BioTherapeutics raises funds to develop new oncology therapies; 14 Apr 2023.