Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0TKFMU
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
TL2-mpeoDM1
|
|||||
| Synonyms |
LmD2
Click to Show/Hide
|
|||||
| Drug Status |
Investigative
|
|||||
| Indication |
In total 2 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Investigative
Lung cancer [ICD11:2C25]
Investigative
|
|||||
| Drug-to-Antibody Ratio |
2.4
|
|||||
| Antibody Name |
Anti-DLL4 mAb TL2 (V207C)
|
Antibody Info | ||||
| Antigen Name |
Delta-like protein 4 (DLL4)
|
Antigen Info | ||||
| Payload Name |
Mertansine DM1
|
Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
|
Target Info | ||||
| Linker Name |
BIMPRO
|
Linker Info | ||||
| Conjugate Type |
Site-specific conjugation through reduced inter-chain cysteines (Cys 207)
|
|||||
If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.