General Information of This Antibody-drug Conjugate (ID: DRG0STJDA)
ADC Name
ALE.P03
Synonyms
ALE.P03
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Organization
Alentis Therapeutics (Originator)
Drug Status
Phase 1/2
Drug-to-Antibody Ratio
4
Structure
Antibody Name
H1L1
 Antibody Info 
Antigen Name
Claudin-1 (CLDN1)
 Antigen Info 
Payload Name
Exatecan
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
Mc-Gly-Gly-Phe-Gly
 Linker Info 
Conjugate Type
Random Cysteines
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Colorectal cancer
1 Trials
Trial ID
NCT07169734; EudraCT2025-521441-24; EUCT2025-521441-24-00
Biliary tract cancer
1 Trials
Trial ID
NCT07169734; EudraCT2025-521441-24; EUCT2025-521441-24-00
Lung cancer
1 Trials
Trial ID
NCT07169734; EudraCT2025-521441-24; EUCT2025-521441-24-00
Cervical cancer
1 Trials
Trial ID
NCT07169734; EudraCT2025-521441-24; EUCT2025-521441-24-00
Urothelial cancer
1 Trials
Trial ID
NCT07169734; EudraCT2025-521441-24; EUCT2025-521441-24-00