Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0SDFSX
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| ADC Name |
ZV-0501
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| Synonyms |
ZV 0501; ZV0501; ZV05-mcMMAF
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| Organization |
Zhejiang Zova Biotherapeutics Inc
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Ovarian cancer [ICD11:2C73]
Investigative
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| Drug-to-Antibody Ratio |
4
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| Structure |
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| Antibody Name |
ZV05
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Antibody Info | ||||
| Antigen Name |
Trophoblast glycoprotein (TPBG)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin F
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Maleimido-caproyl
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Linker Info | ||||
| Conjugate Type |
Cysteine rebridging method.
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| Combination Type |
McMMAF
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