Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0SDEDB
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| ADC Name |
3A11-Exatecan
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| Synonyms |
3A11-Exatecan
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| Organization |
National Cancer Institute.; Binghamton University.; Frederick National Laboratory for Cancer Research.; Manhattan BioSolutions, Inc.
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| Drug Status |
Investigative
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| Antibody Name |
3A11
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Antibody Info | ||||
| Antigen Name |
Fibroblast growth factor receptor 4 (FGFR4)
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Antigen Info | ||||
| Payload Name |
Exatecan
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
mpGlyAsnAsn
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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