General Information of This Antibody-drug Conjugate (ID: DRG0SABRN)
ADC Name
IBI133
Synonyms
IBI133
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Organization
Innovent Biologics (Originator)
Drug Status
Phase 1/2 (discontinued)
Antibody Name
Anti-HER3 mAb
 Antibody Info 
Antigen Name
Receptor tyrosine-protein kinase erbB-3 (HER3)
 Antigen Info 
Payload Name
Exatecan
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Clinical trial identifier
NCT06170190; CTR20241441