Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0RTEJX
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ADC Name |
Tositumomab-Compound 9
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Synonyms |
Tositumomab Compound 9
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Organization |
Rongchang Pharmaceuticals Ltd.
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Drug Status |
Investigative
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Indication |
In total 1 Indication(s)
Non-Hodgkin lymphoma [ICD11:2B33]
Investigative
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Drug-to-Antibody Ratio |
3-3.5
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Antibody Name |
Tositumomab
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Antibody Info | ||||
Antigen Name |
B-lymphocyte antigen CD20 (MS4A1)
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Antigen Info | ||||
Payload Name |
Mertansine DM1
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Payload Info | ||||
Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
Linker Name |
Tositumomab-Compound 9 linker
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Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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