Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0RIGUP
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| ADC Name |
RG-7598
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| Synonyms |
DFRF-4539A; RG7598; DFRF 4539A; RG 7598; DFRF4539A
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| Organization |
Genentech, Inc.; Roche Holding AG; Seagen Inc.
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| Drug Status |
Terminated in phase 1
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| Indication |
In total 1 Indication(s)
Multiple myeloma [ICD11:2A83]
Terminated in phase 1
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| Drug-to-Antibody Ratio |
4
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| Structure |
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| Antibody Name |
MFRF3266A
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Antibody Info | ||||
| Antigen Name |
Fc receptor-like protein 5 (FCRL5)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
Vedotin
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| Puchem SID | ||||||
| ChEBI ID | ||||||
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