Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0QUERC
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| ADC Name |
MET/MET-M114
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| Synonyms |
METxMET M114
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| Drug Status |
Investigative
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| Indication |
In total 3 Indication(s)
Gastric cancer [ICD11:2B72]
Investigative
Lung cancer [ICD11:2C25]
Investigative
Non-small cell lung cancer [ICD11:2C25]
Investigative
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| Drug-to-Antibody Ratio |
3.2
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| Structure |
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| Antibody Name |
Biparatopic METxMET Anti-ody
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Antibody Info | ||||
| Antigen Name |
Hepatocyte growth factor receptor (MET); Hepatocyte growth factor receptor (MET)
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Antigen Info | ||||
| Payload Name |
Maytansine derivative M24
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Succinate-Val-Cit-PABC
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Linker Info | ||||
| Conjugate Type |
Random coupling with lysine on the antibody.
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| Combination Type |
M114
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