General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0QUERC
ADC Name
MET/MET-M114
Synonyms
METxMET M114
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Drug Status
Investigative
Indication
In total 3 Indication(s)
Gastric cancer
Investigative
.
Lung cancer
Investigative
.
Non-small cell lung cancer
Investigative
.
Drug-to-Antibody Ratio
3.2
Structure
Antibody Name
Biparatopic METxMET Anti-ody
 Antibody Info 
Antigen Name
Hepatocyte growth factor receptor (MET); Hepatocyte growth factor receptor (MET)
 Antigen Info 
Payload Name
Maytansine derivative M24
 Payload Info 
Therapeutic Target
Microtubule (MT)
 Target Info 
Linker Name
Succinate-Val-Cit-PABC
 Linker Info 
Conjugate Type
Random coupling with lysine on the antibody.
Combination Type
M114