Payload Information
General Information of This Payload
| Payload ID | PAY0SBXIV |
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|---|---|---|---|---|---|---|
| Name | Maytansine derivative M24 |
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| Synonyms |
M24; HY-115928; CS-0433790
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| Target(s) | Microtubule (MT) | |||||
| Structure |
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| Formula | C37H53ClN4O10 |
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| Isosmiles | CNCCC(=O)N(C)[C@@H](C)C(=O)O[C@H]1[C@H](C)C(=O)N(C)c2cc(cc(OC)c2Cl)C/C(C)=C/C=C/[C@@H](OC)[C@@]2(O)C[C@H](OC(=O)N2)[C@@H](C)[C@@H]2O[C@]21C |
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| PubChem CID | ||||||
| InChI |
InChI=1S/C37H53ClN4O10/c1-20-12-11-13-28(49-10)37(47)19-27(50-35(46)40-37)21(2)32-36(5,52-32)31(51-34(45)23(4)41(7)29(43)14-15-39-6)22(3)33(44)42(8)25-17-24(16-20)18-26(48-9)30(25)38/h11-13,17-18,21-23,27-28,31-32,39,47H,14-16,19H2,1-10H3,(H,40,46)/b13-11+,20-12+/t21-,22+,23+,27+,28-,31+,32+,36+,37+/m1/s1
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| InChIKey |
OWCZLCXJIWNJHS-PXLJFJRMSA-N
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| IUPAC Name |
2-[[2-[3-[[4-[2-(4-chloro-3,5-dimethylphenoxy)ethoxy]phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]acetyl]amino]-N-(4-chloro-3-nitrophenyl)sulfonyl-3-[4-[(4-chlorophenyl)methoxy]phenyl]propanamide
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| Pharmaceutical Properties | Molecule Weight |
749.302 |
Polar area |
168.5 |
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Complexity |
748.3450216 |
xlogp Value |
3.37 |
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Heavy Count |
52 |
Rot Bonds |
8 |
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Hbond acc |
11 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload