Payload Information
General Information of This Payload
| Payload ID | PAY0SBXIV |
|||||
|---|---|---|---|---|---|---|
| Name | Maytansine derivative M24 |
|||||
| Synonyms |
M24; HY-115928; CS-0433790
Click to Show/Hide
|
|||||
| Target(s) | Microtubule (MT) | |||||
| Structure |
|
|||||
| Formula | C44H40Cl3N5O11S |
|||||
| Isosmiles | CC1=CC(=CC(=C1Cl)C)OCCOC2=CC=C(C=C2)CN3CC(=O)N(C3=O)CC(=O)NC(CC4=CC=C(C=C4)OCC5=CC=C(C=C5)Cl)C(=O)NS(=O)(=O)C6=CC(=C(C=C6)Cl)[N+](=O)[O-] |
|||||
| PubChem CID | ||||||
| InChI |
InChI=1S/C44H40Cl3N5O11S/c1-27-19-35(20-28(2)42(27)47)62-18-17-61-33-13-7-30(8-14-33)23-50-25-41(54)51(44(50)56)24-40(53)48-38(43(55)49-64(59,60)36-15-16-37(46)39(22-36)52(57)58)21-29-5-11-34(12-6-29)63-26-31-3-9-32(45)10-4-31/h3-16,19-20,22,38H,17-18,21,23-26H2,1-2H3,(H,48,53)(H,49,55)
|
|||||
| InChIKey |
BBCRCNRTBDZUKL-UHFFFAOYSA-N
|
|||||
| IUPAC Name |
2-[[2-[3-[[4-[2-(4-chloro-3,5-dimethylphenoxy)ethoxy]phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]acetyl]amino]-N-(4-chloro-3-nitrophenyl)sulfonyl-3-[4-[(4-chlorophenyl)methoxy]phenyl]propanamide
|
|||||
| Pharmaceutical Properties | Molecule Weight |
953.2 |
Polar area |
215 |
||
Complexity |
1690 |
xlogp Value |
8.2 |
|||
Heavy Count |
64 |
Rot Bonds |
18 |
|||
Hbond acc |
11 |
Hbond Donor |
2 |
|||
Each Antibody-drug Conjugate Related to This Payload
If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.