Linker Information
General Information of This Linker
| Linker ID |
LIN0KPZTI
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|---|---|---|---|---|---|---|
| Linker Name |
Succinate-Val-Cit-PABC
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C24H37N5O7
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| Isosmiles |
CC(C)C(NC(=O)CCCCC(=O)O)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1
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| InChI |
InChI=1S/C24H37N5O7/c1-15(2)21(29-19(31)7-3-4-8-20(32)33)23(35)28-18(6-5-13-26-24(25)36)22(34)27-17-11-9-16(14-30)10-12-17/h9-12,15,18,21,30H,3-8,13-14H2,1-2H3,(H,27,34)(H,28,35)(H,29,31)(H,32,33)(H3,25,26,36)
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| InChIKey |
ICBOKYYAPJJPTM-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
507.588
|
Polar area
|
199.95
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Complexity
|
36
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xlogp Value
|
0.8365
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Heavy Count
|
36
|
Rot Bonds
|
16
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Hbond acc
|
6
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker
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