Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0QHTLV
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
T2LD5
|
|||||
| Synonyms |
T2-LD5
Click to Show/Hide
|
|||||
| Drug Status |
Investigative
|
|||||
| Indication |
In total 1 Indication(s)
Acute myeloid leukaemia [ICD11:2A60]
Investigative
|
|||||
| Drug-to-Antibody Ratio |
2
|
|||||
| Structure |
|
|||||
| Antibody Name |
Anti-CD46 mAb
|
Antibody Info | ||||
| Antigen Name |
Membrane cofactor protein (CD46)
|
Antigen Info | ||||
| Payload Name |
N-methyl-uncialamycin
|
Payload Info | ||||
| Therapeutic Target |
Human Deoxyribonucleic acid (hDNA)
|
Target Info | ||||
| Linker Name |
Mal-Val-Cit-glucuronide-PABC
|
Linker Info | ||||
| Conjugate Type |
Antibody was engineered to have cysteine residues suitable for selective reduction and site-specific conjugation to the linker-drug.
|
|||||
| Combination Type |
LD5
|
|||||
If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.