Antigen ID	TAR0JMGXV
Antigen Name	Membrane cofactor protein (CD46)
Gene Name	CD46
Gene ID	4179
Synonym	MCP; MIC10; TLX;Trophoblast leukocyte common antigen;CD_antigen=CD46
Sequence	MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHS VSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAV ICVVPYRYLQRRKKKGTYLTDETHREVKFTSL     Click to Show/Hide
Function	Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.     Click to Show/Hide
Uniprot Entry	MCP_HUMAN
HGNC ID	HGNC:6953
KEGG ID	hsa:4179

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	FOR-46	Monomethyl auristatin E	Microtubule (MT)	Undisclosed	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	T2LD6	N-methyl-uncialamycin	Human Deoxyribonucleic acid (hDNA)	Mal-Val-Cit-gucuronide-PEG8-PABC	[2]
ADC Info	T2LD5	N-methyl-uncialamycin	Human Deoxyribonucleic acid (hDNA)	Mal-Val-Cit-glucuronide-PABC	[2]
ADC Info	T2LD4	N-methyl-uncialamycin	Human Deoxyribonucleic acid (hDNA)	Mal-glucuronidase cleavable linker	[2]
ADC Info	T2LD3	N-methyl-uncialamycin	Human Deoxyribonucleic acid (hDNA)	Mal-PEG8	[2]
ADC Info	T2LD2	N-methyl-uncialamycin	Human Deoxyribonucleic acid (hDNA)	Mal-acetic acid	[2]
ADC Info	T2LD1	N-methyl-uncialamycin	Human Deoxyribonucleic acid (hDNA)	Mal-Val-Cit-PABC	[2]
ADC Info	hCD46-19	PNU-159682	DNA topoisomerase 2-alpha (TOP2A)	Hydrophilic cleavable linker 19	[3]
ADC Info	hCD46-25	PNU-159682	DNA topoisomerase 2-alpha (TOP2A)	Alternative linker without basic amines linker 25	[3]
ADC Info	hCD46-26	PNU-159682	DNA topoisomerase 2-alpha (TOP2A)	Maleimide based noncleavable linker 26	[3]
ADC Info	hCD46-29	PNU-159682	DNA topoisomerase 2-alpha (TOP2A)	PNU-thiazole cleavable linker 29	[3]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CD46-ADC	Monomethyl auristatin F	Microtubule (MT)	Mc-Val-Cit-PABC	[4]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	Anti-CD46-antibody drug conjugate (AbbVie)	Undisclosed	Undisclosed	Undisclosed	[5]
ADC Info	CD46 CAB-ADC	Monomethyl auristatin E	Microtubule (MT)	Mc-Val-Cit-PABC	[6]
ADC Info	Anti-CD46 antibody-drug conjugate	Undisclosed	Undisclosed	Undisclosed	[7]

Differential expression pattern of antigen in diseases
The Studied Tissue	Gingival
The Specific Disease	Bacterial infection of gingival
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 8.38E-11; Fold-change: 0.703908544; Z-score: 1.409660016
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Differential expression pattern of antigen in diseases
The Studied Tissue	Brainstem
The Specific Disease	Glioma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.429227564; Fold-change: 0.537938804; Z-score: 0.721028668
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The Studied Tissue	White matter
The Specific Disease	Glioma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.041195236; Fold-change: 0.322049603; Z-score: 0.939766562
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The Studied Tissue	Brainstem
The Specific Disease	Neuroectodermal tumor
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 2.14E-06; Fold-change: -0.887272913; Z-score: -3.02140307
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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The Studied Tissue	Nervous
The Specific Disease	Brain cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 2.67E-09; Fold-change: -0.50863991; Z-score: -0.656287917
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Polycythemia vera
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 2.25E-06; Fold-change: -0.288368336; Z-score: -1.130485375
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The Studied Tissue	Whole blood
The Specific Disease	Myelofibrosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.000562168; Fold-change: -0.59874062; Z-score: -2.342818373
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Myelodysplastic syndromes
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.142710665; Fold-change: -0.009278305; Z-score: -0.02427337
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.417004405; Fold-change: -0.364711624; Z-score: -0.691485641
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Tonsil
The Specific Disease	Lymphoma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.703073108; Fold-change: -0.081074007; Z-score: -0.350311086
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Differential expression pattern of antigen in diseases
The Studied Tissue	Gastric
The Specific Disease	Gastric cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.847618052; Fold-change: 0.03727193; Z-score: 0.032042546
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.017070817; Fold-change: 0.732932922; Z-score: 1.078418431
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Colon
The Specific Disease	Colon cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 5.91E-05; Fold-change: 0.380469184; Z-score: 0.4727659
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 1.14E-17; Fold-change: 1.924168617; Z-score: 1.14472735
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Pancreas
The Specific Disease	Pancreatic cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.001092392; Fold-change: 1.513447346; Z-score: 1.259832246
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 2.36E-05; Fold-change: -0.665800446; Z-score: -1.183182123
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Liver
The Specific Disease	Liver cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.027679576; Fold-change: 0.363461862; Z-score: 0.276840361
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 1.31E-27; Fold-change: 1.243763819; Z-score: 1.366591994
The Expression Level of Disease Section Compare with the Other Disease Section	p-value: 0.40660366; Fold-change: 0.482361267; Z-score: 0.370924624
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Lung
The Specific Disease	Lung cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.26E-06; Fold-change: -0.576313717; Z-score: -0.679695599
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.01135538; Fold-change: 0.060269876; Z-score: 0.042198454
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Melanoma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.771412473; Fold-change: -0.099826381; Z-score: -0.079323978
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Differential expression pattern of antigen in diseases
The Studied Tissue	Muscle
The Specific Disease	Sarcoma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.28E-26; Fold-change: 0.773846497; Z-score: 1.05588489
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 2.19E-89; Fold-change: 1.151672687; Z-score: 59.72088487
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Breast
The Specific Disease	Breast cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.13E-21; Fold-change: 0.94212966; Z-score: 0.883425955
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 1.93E-06; Fold-change: 0.565266766; Z-score: 0.617493213
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Ovarian
The Specific Disease	Ovarian cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.058173688; Fold-change: 0.958820559; Z-score: 0.948514738
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.005100556; Fold-change: 1.867981045; Z-score: 1.435493591
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Cervical
The Specific Disease	Cervical cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 3.59E-05; Fold-change: 0.398581868; Z-score: 1.061231551
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Differential expression pattern of antigen in diseases
The Studied Tissue	Endometrium
The Specific Disease	Uterine cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 4.45E-08; Fold-change: 0.651268408; Z-score: 0.586694714
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.001386759; Fold-change: -1.084459389; Z-score: -3.302283351
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Differential expression pattern of antigen in diseases
The Studied Tissue	Prostate
The Specific Disease	Prostate cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.025785161; Fold-change: -1.400194017; Z-score: -1.010145107
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bladder
The Specific Disease	Bladder cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.10E-06; Fold-change: -1.155080488; Z-score: -3.767143802
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Differential expression pattern of antigen in diseases
The Studied Tissue	Uvea
The Specific Disease	Retinoblastoma tumor
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.07E-07; Fold-change: -1.227800764; Z-score: -3.61724325
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Differential expression pattern of antigen in diseases
The Studied Tissue	Thyroid
The Specific Disease	Thyroid cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.716252042; Fold-change: 0.086813653; Z-score: 0.108638789
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.186989305; Fold-change: -0.083110561; Z-score: -0.14582569
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Adrenal cortex
The Specific Disease	Adrenocortical carcinoma
The Expression Level of Disease Section Compare with the Other Disease Section	p-value: 0.633289833; Fold-change: 0.137666961; Z-score: 0.197382209
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Differential expression pattern of antigen in diseases
The Studied Tissue	Head and neck
The Specific Disease	Head and neck cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 2.90E-17; Fold-change: -0.597220479; Z-score: -1.41282962
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Differential expression pattern of antigen in diseases
The Studied Tissue	Pituitary
The Specific Disease	Pituitary gonadotrope tumor
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.777052443; Fold-change: 0.827456456; Z-score: 0.976653403
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The Studied Tissue	Pituitary
The Specific Disease	Pituitary cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.031803977; Fold-change: 0.923710913; Z-score: 1.043381259
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Thrombocytopenia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.832686746; Fold-change: -0.057527001; Z-score: -0.214289705
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Lupus erythematosus
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 3.58E-08; Fold-change: 0.657798398; Z-score: 0.776961157
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral monocyte
The Specific Disease	Autoimmune uveitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.268981579; Fold-change: -0.788097211; Z-score: -1.094671
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Familial hypercholesterolemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.012127643; Fold-change: -0.452630317; Z-score: -1.221124304
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Differential expression pattern of antigen in diseases
The Studied Tissue	Superior temporal cortex
The Specific Disease	Schizophrenia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.790203375; Fold-change: -0.06654907; Z-score: -0.375172096
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Spinal cord
The Specific Disease	Multiple sclerosis
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.915546695; Fold-change: 0.09360986; Z-score: 0.182069243
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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The Studied Tissue	Plasmacytoid dendritic cells
The Specific Disease	Multiple sclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.081570569; Fold-change: 0.439329311; Z-score: 1.28992025
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peritumoral cortex
The Specific Disease	Epilepsy
The Expression Level of Disease Section Compare with the Other Disease Section	p-value: 0.417381649; Fold-change: -0.265025308; Z-score: -0.381457943
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Cardioembolic Stroke
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 2.40E-09; Fold-change: 0.580472088; Z-score: 1.791544529
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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The Studied Tissue	Peripheral blood
The Specific Disease	Ischemic stroke
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.552805926; Fold-change: -0.234190708; Z-score: -0.433372558
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	White matter
The Specific Disease	HIV
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.240275148; Fold-change: -0.131427024; Z-score: -0.704883021
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Influenza
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.731257687; Fold-change: 0.03959736; Z-score: 0.140774612
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Chronic hepatitis C
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.122038735; Fold-change: -0.142239748; Z-score: -0.762643532
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Sepsis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 5.07E-14; Fold-change: 1.066043128; Z-score: 1.334536752
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Septic shock
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.669659381; Fold-change: -0.100873619; Z-score: -0.119480211
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Pediatric respiratory syncytial virus infection
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.259370163; Fold-change: 0.059703494; Z-score: 0.313224295
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Essential hypertension
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.542996127; Fold-change: -0.067787141; Z-score: -0.296141732
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Myocardial infarction
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.005745256; Fold-change: 0.29915444; Z-score: 0.412858883
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Coronary artery disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.137523933; Fold-change: -0.405907508; Z-score: -1.017096296
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Differential expression pattern of antigen in diseases
The Studied Tissue	Calcified aortic valve
The Specific Disease	Aortic stenosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.197714919; Fold-change: -0.231306915; Z-score: -0.627814427
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Arteriosclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.318721111; Fold-change: -0.05948537; Z-score: -0.380705913
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Differential expression pattern of antigen in diseases
The Studied Tissue	Intracranial artery
The Specific Disease	Aneurysm
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.303923108; Fold-change: -0.225210474; Z-score: -0.62383071
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Immunodeficiency
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.002709524; Fold-change: -0.368772753; Z-score: -1.417606323
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Differential expression pattern of antigen in diseases
The Studied Tissue	Hyperplastic tonsil
The Specific Disease	Apnea
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.275524787; Fold-change: 0.296946411; Z-score: 0.670918559
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Olive pollen allergy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.129648268; Fold-change: -0.427965799; Z-score: -1.478912046
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Differential expression pattern of antigen in diseases
The Studied Tissue	Sinus mucosa
The Specific Disease	Chronic rhinosinusitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.254702844; Fold-change: 0.247904503; Z-score: 0.507187332
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Differential expression pattern of antigen in diseases
The Studied Tissue	Lung
The Specific Disease	Chronic obstructive pulmonary disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.485879094; Fold-change: 0.0313505; Z-score: 0.057677617
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The Studied Tissue	Small airway epithelium
The Specific Disease	Chronic obstructive pulmonary disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.09589383; Fold-change: -0.07173759; Z-score: -0.170483838
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Differential expression pattern of antigen in diseases
The Studied Tissue	Nasal and bronchial airway
The Specific Disease	Asthma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.000131762; Fold-change: -0.089461495; Z-score: -0.041457427
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Differential expression pattern of antigen in diseases
The Studied Tissue	Nasal Epithelium
The Specific Disease	Human rhinovirus infection
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.122167519; Fold-change: -0.017114443; Z-score: -0.071086343
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Differential expression pattern of antigen in diseases
The Studied Tissue	Lung
The Specific Disease	Idiopathic pulmonary fibrosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.003669437; Fold-change: -0.385869112; Z-score: -2.152560165
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Differential expression pattern of antigen in diseases
The Studied Tissue	Gingival
The Specific Disease	Periodontal disease
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 9.14E-08; Fold-change: 0.630577142; Z-score: 1.326735073
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Differential expression pattern of antigen in diseases
The Studied Tissue	Gastric antrum
The Specific Disease	Eosinophilic gastritis
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.155743103; Fold-change: -0.967545701; Z-score: -3.868138794
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Differential expression pattern of antigen in diseases
The Studied Tissue	Liver
The Specific Disease	Liver failure
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.073131867; Fold-change: -0.178592468; Z-score: -0.731202858
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Differential expression pattern of antigen in diseases
The Studied Tissue	Colon mucosal
The Specific Disease	Ulcerative colitis
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.029944599; Fold-change: -0.052529398; Z-score: -0.182692337
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Differential expression pattern of antigen in diseases
The Studied Tissue	Rectal colon
The Specific Disease	Irritable bowel syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.060695751; Fold-change: -0.215786858; Z-score: -0.546172245
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Atopic dermatitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.869581361; Fold-change: -0.040348422; Z-score: -0.103252893
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Psoriasis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.67E-09; Fold-change: -0.212055107; Z-score: -0.333886582
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 1.03E-33; Fold-change: 1.771394462; Z-score: 3.707265334
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Vitiligo
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.040366246; Fold-change: 0.218617502; Z-score: 0.803320612
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin from scalp
The Specific Disease	Alopecia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.830917982; Fold-change: 0.041500034; Z-score: 0.115283942
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Sensitive skin
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.801117389; Fold-change: 0.196256809; Z-score: 0.318309595
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Differential expression pattern of antigen in diseases
The Studied Tissue	Synovial
The Specific Disease	Osteoarthritis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.460015082; Fold-change: 0.298748717; Z-score: 0.589451308
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Arthropathy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.493452252; Fold-change: 0.391335298; Z-score: 0.647050927
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Arthritis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.67E-09; Fold-change: 0.363363646; Z-score: 1.110286306
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Differential expression pattern of antigen in diseases
The Studied Tissue	Synovial
The Specific Disease	Rheumatoid arthritis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 6.83E-08; Fold-change: 1.851988653; Z-score: 5.795924057
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Differential expression pattern of antigen in diseases
The Studied Tissue	Pheripheral blood
The Specific Disease	Ankylosing spondylitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.688167358; Fold-change: 0.006434867; Z-score: 0.013135083
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Osteoporosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.564133274; Fold-change: -0.07807106; Z-score: -0.184839448
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Differential expression pattern of antigen in diseases
The Studied Tissue	Endometrium
The Specific Disease	Endometriosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.558575154; Fold-change: -0.10188877; Z-score: -0.203040928
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bladder
The Specific Disease	Interstitial cystitis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.29E-05; Fold-change: -1.085915149; Z-score: -4.821287908
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Differential expression pattern of antigen in diseases
The Studied Tissue	Myometrium
The Specific Disease	Preterm birth
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.891728016; Fold-change: -0.040534682; Z-score: -0.031259863
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Acute myelocytic leukemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.828155496; Fold-change: 0.006223455; Z-score: 0.00922217
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Myeloma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.013507479; Fold-change: 0.311891089; Z-score: 0.768041415
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The Studied Tissue	Peripheral blood
The Specific Disease	Myeloma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.455430643; Fold-change: 0.109484437; Z-score: 0.690359506
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Differential expression pattern of antigen in diseases
The Studied Tissue	Oral
The Specific Disease	Oral cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.752424899; Fold-change: -0.08446316; Z-score: -0.094247236
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.000222514; Fold-change: -0.490743368; Z-score: -0.565120323
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Differential expression pattern of antigen in diseases
The Studied Tissue	Esophagus
The Specific Disease	Esophagal cancer
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.000728784; Fold-change: -1.317187091; Z-score: -3.393291464
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Differential expression pattern of antigen in diseases
The Studied Tissue	Rectal colon
The Specific Disease	Rectal cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.00023817; Fold-change: 1.029900828; Z-score: 3.250890295
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.865518715; Fold-change: 0.04816993; Z-score: 0.176698215
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Skin cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 1.25E-08; Fold-change: -0.796471264; Z-score: -1.019160905
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 1.63E-16; Fold-change: 0.718420556; Z-score: 0.957001681
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Kidney
The Specific Disease	Renal cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.426240571; Fold-change: -0.625150126; Z-score: -0.575728541
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 2.93E-22; Fold-change: -0.964449984; Z-score: -1.709038824
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Differential expression pattern of antigen in diseases
The Studied Tissue	Urothelium
The Specific Disease	Ureter cancer
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.322791725; Fold-change: 0.052678278; Z-score: 0.170052274
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Differential expression pattern of antigen in diseases
The Studied Tissue	Adipose
The Specific Disease	Simpson golabi behmel syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.193711937; Fold-change: -0.057538755; Z-score: -2.041395756
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Differential expression pattern of antigen in diseases
The Studied Tissue	Perituberal
The Specific Disease	Tuberous sclerosis complex
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.007975194; Fold-change: -1.128277419; Z-score: -2.472861308
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Differential expression pattern of antigen in diseases
The Studied Tissue	Bone marrow
The Specific Disease	Anemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.33185262; Fold-change: 0.050267252; Z-score: 0.130592026
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Sickle cell disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.069431731; Fold-change: 0.169617297; Z-score: 0.960503162
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Thrombocythemia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 5.49E-05; Fold-change: -0.353738091; Z-score: -1.49208135
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Scleroderma
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.496682096; Fold-change: 0.076922451; Z-score: 0.335421688
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Differential expression pattern of antigen in diseases
The Studied Tissue	Salivary gland
The Specific Disease	Sjogren syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.200725948; Fold-change: -0.411308955; Z-score: -1.243340818
The Expression Level of Disease Section Compare with the Adjacent Tissue	p-value: 0.16275676; Fold-change: 0.384364396; Z-score: 0.769626944
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Differential expression pattern of antigen in diseases
The Studied Tissue	Peripheral blood
The Specific Disease	Behcet disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.685414542; Fold-change: -0.08317072; Z-score: -0.203985268
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Autosomal dominant monocytopenia
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.019466651; Fold-change: -0.673514528; Z-score: -1.870305231
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Differential expression pattern of antigen in diseases
The Studied Tissue	Liver
The Specific Disease	Type 2 diabetes
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.800283378; Fold-change: 0.043134976; Z-score: 0.195641261
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Differential expression pattern of antigen in diseases
The Studied Tissue	Vastus lateralis muscle
The Specific Disease	Polycystic ovary syndrome
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.356408531; Fold-change: -0.069784836; Z-score: -0.372472004
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Differential expression pattern of antigen in diseases
The Studied Tissue	Subcutaneous Adipose
The Specific Disease	Obesity
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.81828408; Fold-change: 0.013741984; Z-score: 0.043893944
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Differential expression pattern of antigen in diseases
The Studied Tissue	Biceps muscle
The Specific Disease	Pompe disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.241546418; Fold-change: -0.150648799; Z-score: -0.671906177
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Batten disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.133967695; Fold-change: -0.310347858; Z-score: -1.838245141
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Autism
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.495709665; Fold-change: 0.315113381; Z-score: 0.327079225
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Anxiety disorder
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.329795277; Fold-change: 0.052223587; Z-score: 0.125407227
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Differential expression pattern of antigen in diseases
The Studied Tissue	Substantia nigra
The Specific Disease	Parkinson disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.002744764; Fold-change: -0.422962934; Z-score: -2.063958601
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Huntington disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.206294363; Fold-change: 0.342945229; Z-score: 0.640067955
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Differential expression pattern of antigen in diseases
The Studied Tissue	Entorhinal cortex
The Specific Disease	Alzheimer disease
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.661914585; Fold-change: 0.037775445; Z-score: 0.127309255
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Differential expression pattern of antigen in diseases
The Studied Tissue	Whole blood
The Specific Disease	Seizure
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.894467461; Fold-change: 0.094642134; Z-score: 0.118494583
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Differential expression pattern of antigen in diseases
The Studied Tissue	Skin
The Specific Disease	Lateral sclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.355932538; Fold-change: -0.11927369; Z-score: -0.742668785
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The Studied Tissue	Cervical spinal cord
The Specific Disease	Lateral sclerosis
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.669801254; Fold-change: -0.088739524; Z-score: -0.347261305
Disease-specific Antigen Abundances		Click to View the Clearer Original Diagram
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Differential expression pattern of antigen in diseases
The Studied Tissue	Muscle
The Specific Disease	Muscular atrophy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.771903781; Fold-change: 0.019034801; Z-score: 0.054752105
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Differential expression pattern of antigen in diseases
The Studied Tissue	Muscle
The Specific Disease	Myopathy
The Expression Level of Disease Section Compare with the Healthy Individual Tissue	p-value: 0.386694954; Fold-change: 0.139590715; Z-score: 0.230481518
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Ref 1	FOR46 in Combination With Enzalutamide in Patients With Metastatic Castration Resistant Prostate Cancer; NCT05011188.
Ref 2	Uncialamycin-based antibody-drug conjugates: Unique enediyne ADCs exhibiting bystander killing effect. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2107042118. doi: 10.1073/pnas.2107042118.
Ref 3	Evaluation of PNU-159682 antibody drug conjugates (ADCs). Bioorg Med Chem Lett. 2020 Dec 15;30(24):127640. doi: 10.1016/j.bmcl.2020.127640. Epub 2020 Oct 28.
Ref 4	Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells. J Clin Invest. 2016 Dec 1;126(12):4640-4653. doi: 10.1172/JCI85856. Epub 2016 Nov 14.
Ref 5	Introduction to basic information on anti-CD46- antibody drug conjugates(AbbVie).
Ref 6	Conditionally active biologics (CAB): A novel class of molecules targeting solid tumors. Cancer Res (2020) 80 (16_Supplement): 4560.
Ref 7	Introduction to basic information on anti-CD46 antibody-drug conjugate(University of California San Francisco/Washington University in St Louis).