General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0PXBVI
ADC Name
RC68-PY-Val-Cit-PABC-MMAE
Synonyms
RC68 PY VC PAB MMAE
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Organization
RemeGen Co., Ltd.
Drug Status
Investigative
Indication
In total 1 Indication(s)
Pancreatic cancer
Clinical candidate
.
Drug-to-Antibody Ratio
4
Structure
Antibody Name
RC68
 Antibody Info 
Antigen Name
Epidermal growth factor receptor (EGFR)
 Antigen Info 
Payload Name
Monomethyl auristatin E
 Payload Info 
Therapeutic Target
Microtubule (MT)
 Target Info 
Linker Name
PY-VC-PABC
 Linker Info 
Conjugate Type
PY-VC-PABC was designed as a linker that covalently connected to thiol groups with a coupling agent to make the thiol bridges linking two heavy chains or the heavy with light chains in a given antibody.
Combination Type
PY-VC-PABC-MMAE