Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0PXBVI
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| ADC Name |
RC68-PY-Val-Cit-PABC-MMAE
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| Synonyms |
RC68 PY VC PAB MMAE
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| Organization |
RemeGen Co., Ltd.
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| Drug Status |
Clinical candidate
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| Indication |
In total 1 Indication(s)
Pancreatic cancer [ICD11:2C10]
Clinical candidate
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| Drug-to-Antibody Ratio |
4
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| Structure |
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| Antibody Name |
RC68
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Antibody Info | ||||
| Antigen Name |
Epidermal growth factor receptor (EGFR)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
PY-VC-PABC
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Linker Info | ||||
| Conjugate Type |
PY-VC-PABC was designed as a linker that covalently connected to thiol groups with a coupling agent to make the thiol bridges linking two heavy chains or the heavy with light chains in a given antibody.
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| Combination Type |
PY-VC-PABC-MMAE
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